A simple way to auto-start

[GelatoSosolato]

PBO.txt

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@echo off
"C:\Program Files\PboTuner2\PBO2tuner.exe" -10 -10 -10 -10 -10 -10 -10 -10
exit

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Open and point your path and values
Rename txt to bat
Win + R, type shell:startup and click OK
Create a file shortcut
Done!