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# Figures
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::: {#fig-model}
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- ![ ] ( figures/v2/Figure1.pdf )
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+ ![ ] ( figures/v2/Figure1.pdf ) {width=98%}
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Pyro&thinsp ; -Velocity is a fully generative Bayesian method with uncertainty
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estimation of velocity vector fields and shared latent time, based on raw counts
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:::
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::: {#fig-model-results}
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- ![ ] ( figures/v2/Figure2.png )
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+ ![ ] ( figures/v2/Figure2.png ) {width=98%}
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Pyro&thinsp ; -Velocity outperforms other RNA-velocity methods and accurately
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predicts cell lineage trajectories. ** a,b** , RNA Velocity model comparisons from
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:::
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::: {#fig-lineage-tracing}
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- ![ ] ( figures/v2/Figure3.png )
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+ ![ ] ( figures/v2/Figure3.png ) {width=98%}
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Pyro&thinsp ; -Velocity accurately predicts cell fate choices and lineage
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trajectory in human LARRY barcoded hematopoietic cells. Systematic benchmarking
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# Extended Data Figures
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::: {#extfig-graphical-models}
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- ![ ] ( figures/v2/Supplementary-Figure1.pdf )
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+ ![ ] ( figures/v2/Supplementary-Figure1.pdf ) {width=98%}
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Graphical representations detail the generative process of the
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Pyro&thinsp ; -Velocity models and highlight their differences. ** a** ,
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:::
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::: {#extfig-model-results}
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- ![ ] ( figures/v2/Supplementary-Figure2.png )
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+ ![ ] ( figures/v2/Supplementary-Figure2.png ) {width=98%}
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Extended version of @fig-model-results for evaluating Pyro&thinsp ; -Velocity
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(Model 1) and scVelo on the PBMC and pancreas datasets. ** a** , Left figure shows
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:::
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::: {#extfig-model-2-result}
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- ![ ] ( figures/v2/Supplementary-Figure3.png )
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+ ![ ] ( figures/v2/Supplementary-Figure3.png ) {width=98%}
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Extension of @fig-model-results , Pyro&thinsp ; -Velocity (Model 2) outperforms
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scVelo on PBMC and pancreas datasets. Same format as in @fig-model-results and
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@extfig-model-results .
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:::
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::: {#extfig-lineage-tracing}
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- ![ ] ( figures/v2/Supplementary-Figure4.png )
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+ ![ ] ( figures/v2/Supplementary-Figure4.png ) {width=98%}
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Extension of @fig-lineage-tracing , Pyro&thinsp ; -Velocity (Model 1 for uni-fate
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data, Model 2 for bi-fate and multi-fate data) outperforms Cytotrace on
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:::
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::: {#extfig-lineage-tracing-2}
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- ![ ] ( figures/v2/Supplementary-Figure5.png )
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+ ![ ] ( figures/v2/Supplementary-Figure5.png ) {width=98%}
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Extension of [ @fig-lineage-tracing ] presenting an extended comparison of
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Pyro&thinsp ; -Velocity and scVelo on scRNA-seq datasets with lineage barcoding
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