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7 | 7 |
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8 | 8 | *A Statistical Toolbox for QTL Analysis*
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9 | 9 |
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10 |
| -`BigRiverQTL.jl` is a user-friendly Julia package that supports |
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| -efficient and interpretable quantitative trait locus (QTL) |
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| -analysis. This comprehensive toolbox encompasses three core components |
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| -tailored to streamline the entire QTL analysis workflow: |
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| -preprocessing, genomic scanning, and result visualization. |
| 10 | +`BigRiverQTL.jl` is a package that makes it easier to perform |
| 11 | +quantitative trait locus (QTL) analysis in Julia. It consists of |
| 12 | +three components streamline the QTL analysis workflow: |
| 13 | +preprocessing, genome scans, and visualization. |
15 | 14 |
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16 | 15 | - **Preprocessing:** The preprocessing functions are designed to
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17 | 16 | seamlessly import and convert genomic data into an efficient and
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18 | 17 | memory-conservative format. This component also offers function
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19 | 18 | capabilities for quickly calculating kinship matrices, ensuring data
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20 | 19 | readiness for subsequent analysis phases.
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21 | 20 |
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| -- **Genomic Scanning:** `BigRiverQTL.jl` provides advanced genomic |
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| - scanning capabilities through `BulkLMM.jl` for swift single-trait |
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| - scans, which surpass other methods in terms of computational |
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| - speed. For analyses involving multiple traits, the package employs |
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| - `FlxQTL.jl`, a cutting-edge approach that detects complex trait |
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| - interrelations. |
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| - |
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| -- **Result Visualization:** The third component of `BigRiverQTL.jl` |
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| - enriches the analytical experience by offering plotting tools |
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| - designed to illustrate the outcomes of genomic scans. The plotting |
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| - functions are useful for interpreting the results and aid in the |
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| - derivation of meaningful conclusions |
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| - |
| 21 | +- **Genome Scans:** We provide the capabilities to perform a large |
| 22 | + number of univariate genome scans using |
| 23 | + [`BulkLMM.jl`](https://github.com/senresearch/BulkLMM.jl). For |
| 24 | + analyses involving multiple traits, we provide an interface to |
| 25 | + [`FlxQTL.jl`](https://github.com/senresearch/FlxQTL.jl) to analyze |
| 26 | + longitudinal traits and complex trait correlations. |
| 27 | + |
| 28 | +- **Visualization:** The third component of the package offers |
| 29 | + plotting tools designed to visualize genome scans including eQTL |
| 30 | + scans using the |
| 31 | + [`BigRiverQTLPlots.jl`](https://github.com/senresearch/BigRiverQTLPlots.jl) |
| 32 | + package. |
35 | 33 |
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36 | 34 | ## Installation
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37 | 35 |
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