A lightweight browser-based mRNA molecular weight calculator
for synthetic RNA design and analysis. Ideal for researchers in
RNA therapeutics, molecular biology and synthetic biology.
This web-based tool allows you to calculate key properties of messenger RNA (mRNA) sequences.
It supports custom RNA sequences with optional 5'-Cap structures (e.g., CleanCap®), Ψ (N1-Methylpseudouridine) substitutions, and provides:
- Molecular formula and exact mass (free acid / sodium salt forms)
- Charge estimation
- Nucleotide composition
- Export functionality
⚙️ Built entirely in HTML, CSS, and JavaScript – no backend required.
For feedback, suggestions, or bug reports, please contact:
📨 bitlabtools@proton.me
This tool is intended for educational and academic purposes only.
It is provided "as is" without any express or implied warranty.
The author assumes no responsibility for the accuracy, completeness, or consequences of its use.
The calculations are based on publicly available average molecular weights of monophosphate nucleotides (e.g., AMP, GMP, UMP, CMP) and commonly accepted chemical rules.
No proprietary analytical methods or patented procedures are implemented.
No entered sequences are stored, logged, or transmitted.
All processing is performed locally in your browser.
No cookies are used and no personal data is stored.
CleanCap® is a registered trademark of TriLink BioTechnologies.
This tool is not affiliated with, sponsored by, or endorsed by TriLink in any way.
- Open for academic/non-commercial use.
- Do not use this tool for commercial, clinical, or therapeutic applications without consulting the respective trademark holders and legal frameworks.