This project aims to develop a framework that autonomously navigates multiple drug-related online resources to retrieve data regarding drugs interactions and EMA drugs adverse reactions reports. Initially designed to browse the EMA database of EudraVigilance (European Database of suspected adverse drug reaction reports), the project has now been expanded to incorporate additional functionalities.
EudraVigilance is a data processing network and management system for reporting and evaluating suspected adverse drug reactions (ADRs) during the development and following the marketing authorization of medicinal products in the European Economic Area (EEA). The system supports the electronic exchange of suspected adverse drug reaction reports known as Individual Case Safety Reports (ICSRs) between the European Medicines Agency (EMA), National Competent Authorities (NCAs), Marketing Authorization Holders (MAHs), and sponsors of clinical trials in the EEA.
The script automates navigation to https://www.adrreports.eu/en/search.html, where it searches for target drugs specified in resources/drugs_to_search.txt. Upon locating the target drugs, the script downloads associated data reports in the form of Excel files. The implementation uses ChromeDriver to simulate user interaction with the browser, ensuring smooth and accurate navigation of the EMA database.
Search page at https://www.adrreports.eu/en/search.html#
The suspected adverse drug reaction report for Abasaglar
The installation process for Windows is fully automated. Simply run the script start_on_windows.bat to begin. During its initial execution, the script installs portable Python, necessary dependencies, minimizing user interaction and ensuring all components are ready for local use.
On Windows, run start_on_windows.bat to launch the application. Please note that some antivirus software, such as Avast, may flag or quarantine python.exe when called by the .bat file. If you encounter unusual behavior, consider adding an exception in your antivirus settings.
The main UI allows you to either run a search from file or to use the input text box to insert drug names. Since the script is based on Chromedriver, your need to have Google Chrome browser installed in your system! The correct driver version will be automatically installed, or loaded from the cache if present (default location is home/.wdm).
Setup and Maintenance: you can run setup_and_maintenance.bat to start the external tools for maintenance with the following options:
- Update project: check for updates from Github
- Remove logs: remove all logs file from resources/logs
This folder is used to organize the main data for the project, including downloaded files saved in resources/download and the app logs located in resources/logs. The resources/drugs_to_search.txt file contains the names of the drugs you want to download the reports for.
Environmental variables are stored in the app folder (within the project folder). For security reasons, this file is typically not uploaded to GitHub. Instead, you must create this file manually by copying the template from resources/templates/.env and placing it in the app directory.
| Variable | Description |
|---|---|
| None | Placeholder for future environmental variables |
This project is licensed under the terms of the MIT license. See the LICENSE file for details.